OCULAR BIOLOGY & IMAGING LAB at EAST TENNESSEE STATE UNIVERSITY

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Mark Kleinman

June 24, 2014 160 × 224 About Our Research

Mark Kleinman, MD
Principal Investigator

Deciphering age-related transcriptomic changes in the mouse retinal pigment epithelium
Histone deficiency and hypoacetylation in the aging retinal pigment epithelium
Unraveling Histone Loss in Aging and Senescence
Long-Term Evaluation of Retinal Morphology and Function in Rosa26-Cas9 Knock-In Mice
Targeting of miR-33 ameliorates phenotypes linked to age-related macular degeneration
Imaging data on characterization of retinal autofluorescent lesions in a mouse model of juvenile neuronal ceroid lipofuscinosis (CLN3 disease)
Loss of CLN3, the gene mutated in juvenile neuronal ceroid lipofuscinosis, leads to metabolic impairment and autophagy induction in retinal pigment epithelium
Vision loss in juvenile neuronal ceroid lipofuscinosis (CLN3 disease)
Complement Activation and Inhibition in Retinal Diseases
Therapeutic Approaches to Histone Reprogramming in Retinal Degeneration

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