OCULAR BIOLOGY & IMAGING LAB at EAST TENNESSEE STATE UNIVERSITY

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  • The Kleinman Laboratory for Ocular Biology and Imaging
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Molecular Imaging in the Human Eye

October 13, 2014 S. Lee Ware

We are working hard to develop new diagnostic imaging technologies to combat AMD.

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Previous PostJennifer BrownNext PostSubhash C. Prajapati, PhD

Lab Contact

East Tennessee State University
James H. Quillen College of Medicine
Bldg 119 Rm 1-04
Johnson City, TN 37614
Department of Surgery
Ph (423) 439-5969
Fax (423) 439-6251
Email: kleinman@etsu.edu

Regarding Open Positions & Inquiries

We are always looking for highly self-motivated and creative individuals with an M.D. or doctoral-level training in the biological sciences. Our laboratory has several exciting and advanced avenues of investigation in non-invasive molecular-scale imaging modalities for aging retinal diseases and a program focused on dissecting the role of epigenetic regulation of inflammation and cell death in photoreceptors and retinal pigment epithelium.

Depending on project assignment, the candidate will gain critical skills in novel techniques in multi-modal small animal imaging, custom fluorophore bio-conjugate engineering, mass spectrometry based proteomics, massively parallel sequencing, bioinformatics pipelines, analyses to assess histone binding and modifications in genomic DNA, and numerous other advanced molecular biology techniques. Significant experience will be offered in the design and interpretation of experiments as well as grantsmanship to prepare the candidate for a successful independent career as a principal investigator in the biomedical sciences.

Candidates must be willing and comfortable working with rodents. Two year of eligibility and commitment as postdoctoral scholar is required. Preference will be given to those with experience in ocular biology specifically in the posterior segment, vascular biology, vision, neuroscience or aging research. Salary will be based on University guidelines for postdoctoral fellows, and will be commensurate with experience.

Interested applicants please submit CV, brief statement of interest and career goals, contact information and three references. In the CV, please list your technical expertise, especially in animal dissection and surgeries, optical coherence tomography, electrophysiology, histology/imaging/microscopy, mass spectrometry, massively parallel sequencing, bio-informatics, or other advanced techniques in molecular biology.

  • The Kleinman Laboratory for Ocular Biology and Imaging
  • About Our Research
  • Team
    • Mark Kleinman
    • Researchers
    • Staff
    • Alumni
  • Publications

Most Recent Lab News

  • Sushil Dubey, PhD
  • Subhash C. Prajapati, PhD
  • Molecular Imaging in the Human Eye
  • Jennifer Brown
  • Jacob Roney

Online Resources

  • Ambati Lab Lab of J. Ambati
  • Webvision – University of Utah Online Retina Texbook

RSS PubMed Record

  • Loss of CLN3, the gene mutated in juvenile neuronal ceroid lipofuscinosis, leads to metabolic impairment and autophagy induction in retina pigment epithelium. Zhong Y, Mohan K, Liu J, Al-Attar A, Lin P, Flight RM, Sun Q, Warmoes MO, Deshpande RR, Liu H, Jung KS, Mitov MI, Lin N, Butterfield DA, Lu S, Liu J, Moseley HNB, Fan TWM, Kleinman ME, Wang QJ

RSS Medscape Eye

  • Cardio Risk Increases With Diabetic Retinopathy Progression August 3, 2020
    The strong correlation between severity of diabetic retinopathy and cardiovascular events could help ophthalmologists motivate affected patients with type 2 diabetes to see a primary care provider. Medscape Medical News
  • The Dangers of an Unwitnessed Pandemic July 31, 2020
    This, Dr. Weiss wrote in his day four entry, is the reality of the disease: 'You really can't understand till you see it…and that's the problem. Nobody is seeing it.' Undark
  • Med Students and Doctors Shouldn't Sell Advice July 29, 2020
    Increased competition among medical school applicants has led to a boom in premed advising companies. Here's why med students and faculty shouldn't sell advice through these services. Medscape Med Students
  • What Does the Case Fatality Rate Really Tell Us? July 29, 2020
    There are two big problems with the case fatality rate metric, says Dr F. Perry Wilson. What we really want to know is the infection fatality rate. What's the difference? Medscape
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